|Title of Profil||Innovative chitosan-based biomimetic scaffold for wound repair and tissue engineering|
12 BE 0324 3OHZ
|Country of origin||Belgium|
|Entry/Update||2012-06-29 / 2013-05-22|
AbstractA research team of a Belgian University has developed a tridimensional-layered chitosan scaffold. This scaffold offers potential applications in wound repair, tissue engineering.The research team is looking for collaboration with companies for joint development, testing and in vivo evaluation.
The primary function of a wound dressing is the protection against environment. For extended wounds or hard-to-heal ulcers, additionnals properties would be highly desirable, such as the stimulation of the healing process or the improvement of the overall quality of the repaired tissue.This research team of scientists have developed a tridimensional-layered chitosan scaffold made of : o a porous support (sponge) allowing absorbance of exudates;o a nanofiber membrane allowing adhesion and proliferation of endothelial cells, keratinocytes and fibroblasts. The nanofiber membrane is electrospun onto the porous support layer. The whole device is stabilized by the fusion of the 2 layers. For illustration, see picture.Innovative Aspects:- Fully biocompatible - Allows adhesion, growth and differentiation of the main cell types of the skin - Progressive integration and remodeling of the nanofibrillar compartment in vivo - Stimulation of the closure of skin wounds in vivo - Easy manipulation of the whole device - Possibility to peel off the support (sponge) layer, keeping the wound bed intact during the renewal of the dressing and allowing use of chitosan nanofibrillar scaffold as a guide to facilitate tissue repair.
- Medicine, Human Health
- Medical Technology / Biomedical Engineering
- Single Use Products and Consumer Goods
- Other Medical/Health Related
- Disposable products
Stage of development
Available for demonstration
Patent Rights (IPR)
Patent(s) applied for but not yet granted
| ||WO 2011/151225A1 |
- License Agreement
- Joint further development
- Testing of new applications
- Adaptation to specific needs
Type of partner sought: companies involved in wound dressing developmentSpecific area of activity of the partner: wound dressingTask to be performed by the partner sought: in vivo testing and further development
Research institute/University Org. Size: 11-50
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