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AbstractAn international consortia coordinated by an Estonian SME is looking for additional SME partners to identify new sex-specific biomarkers of sperm cells for animal breeding and develop novel methods of gender selection for the cattle breeding industry and reproductive veterinary medicine. Two end-user SMEs for validation of sex-specific antibodies are sought.DetailsIdentification of new sex-specific biomarkers of sperm cells enabling to develop novel high-throughput method of sperm sex-selection for the animal husbandry (cattle breeding) and reproductive veterinary medicine. The project consortium already has the necessary research capacity in immunisation of laboratory animals with X- and Y-chromosome fractionated bovine sperm cells, production of polyclonal anti-sperm antibodies, application of phage display technology for screening antibody libraries and antibody epitope mapping, characterisation of the phage DNA (Deoxyribonucleic acid) library by next generation sequencing, bioinformatic analysis and proteome analysis of sex-selected sperm cells.In order to complete the consortium, additional partners with the following competences and roles in the project are sought: - SME partner, cattle breeding farm – validation of the gender selection methods in real life environment; - SME partner, specialized in production and distribution of normal and sex-selected cattle sperm – validation of the method in laboratory environment. Technical Specifications / Specific technical requirements: Call information: - Call identifier: FP7-SME-2012-1 - Deadline: 6 December 2011 Proposal development stage: - Under preparation, not yet submitted Requested EU funding: - Approximately €1.1 Million Two end-user SMEs for validation of sex-specific antibodies are sought.
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